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Search Results for " dopamine d2 receptor antagonist-1 "

10

Compounds

Cat No. Product Name Synonyms Targets
T11077 Dopamine D2 receptor antagonist-1 Others
Dopamine D2 Receptor Antagonist-1 functions as a negative allosteric modulator (NAM) of the dopamine D2 receptor (D2R), demonstrating sub-millimolar affinity.
T7352 Pridopidine ACR16,ASP2314,FR310826 Dopamine Receptor
Pridopidine (FR310826), a dopamine (DA) stabilizer, acts as a low affinity dopamine D2 receptor (D2R) antagonist, improves motor performance and shows neuroprotective effects in Huntington disease R6/2 mouse model.
T9100 BP 897 2-Naphthalenecarboxamide, N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]- Dopamine Receptor
BP 897 (2-Naphthalenecarboxamide, N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]-) is a potent and selective dopamine D3 receptor agonist, and a weak dopamine D2 receptor antagonist, with Kis of 0.92 nM and 61 nM for D3 ...
T24885 Tiospirone BMY 13859-1 Dopamine Receptor , 5-HT Receptor
Tiospirone (BMY 13859-1 free base) is a 5-HT2 receptor antagonist and dopamine blocker that inhibits D2, 5-HT1a, 5-HT7, and sigma receptors.Tiospirone is used in the study of neurological disorders such as schizophrenia.
T36949 Niaprazine 5-HT Receptor , Adrenergic Receptor , Histamine Receptor
Niaprazine is a histamine H1-receptor antagonist with marked sedative properties. Niaprazine has antihistamine and antiserotonin activities and can be used for sleep disorder research[1][2]. Niaprazine exhibits a low aff...
T60943 Tiapride
Tiapride is an atypical neuroleptic agent without propensity for causing catalepsy and sedation. Tiapride is a selective antagonist of dopamine D2-receptor with IC 50 values of 1440, 45.8, >100, and 11.7 μM for D1; D2; D...
T22044 BGC 20-761
BGC20-761 is a selecvtive 5-HT6 and dopamine receptor antagonist (human receptor K i values: 5-HT6 (20 nM), 5-HT2A (69 nM), D2 (140 nM). BGC20-761 is a tryptamine analog with a high affinity for 5-HT(6) receptors, that c...
T63115 Perphenazine dihydrochloride
Perphenazine dihydrochloride is an orally active dopamine receptor and histamine-1 receptor antagonist that acts on D2 (Ki: 0.56 nM), D3 (Ki: 0.43 nM), 5-HT2A (Ki: 0.6 nM). Perphenazine dihydrochloride is also able to bi...
T61476 Thioridazine
Thioridazine is a chemical compound characterized by its potent anti-psychotic and anti-anxiety activities. As an antagonist of the dopamine receptor D2 family proteins, it exhibits a strong inhibitory effect on the PI3K...
T83909 6-hydroxy Buspirone BMY 28674,BMS-52821
6-Hydroxy Buspirone, an active metabolite of the anxiolytic compound buspirone, is produced via the cytochrome P450 (CYP) isoform CYP3A4. This compound exhibits affinity for the serotonin (5-HT) receptor subtype 5-HT1A, ...
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